The most common question that many cannabis users ask is about the best marijuana strains. Different weed varieties have varying properties that can qualify them as either bad or good. But we have to remember that people react to cannabis differently, depending on their genetic makeup.
So, what are the best strains of weed? People take weed for different reasons. Unless we know why you need it, we cannot say what the best strains of marijuana are. For instance, you might need the best weed strains for productivity or the best euphoric strains. Other people would be looking for best tasting weeds or the strongest cannabis strains that will hit them hard and fast.
You can dig deeper in the above-listed categories to find specific examples of top cannabis strains that meet your needs. They are well-vetted and recommended by experts as the best weed strains for the intended effects.
Best Cannabis Strains Most Popular 2021
In this section, we will briefly describe the top 20 weed strains in Colorado. If you are a resident or plan to visit this state for a vacation, you can get yourself the best weed strain from this list.
Girl Scout Cookies
Girl Scout Cookies is at the top of our list of the best cannabis weed strains for the right reasons. It is a hybrid strain with a high THC level of up to 28%. If you are looking for the best weed strain that is highly potent, Girl Scout Cookies should come as your number one.
This Indica-dominant weed strain has a high characterized by a happy, euphoria, and couch-lock. It is the top marijuana strain desirable if you need to relax after a long day at work. Medical cannabis users can also benefit from GSC to relieve stress, anxiety, depression, etc.
Durban Poison
Durban Poison comes as the second-best strain of marijuana but should have been the first on the list. This 100% Sativa strain has a THC level of about 24% but still gives users a heavy blow to the head. Its potency makes it one of the top strains of weed in the world.
Durban Poison hits with a strong, happy head high that leaves you more creative and energetic to go about your daily businesses. Medicinally, this is the best weed strain for relieving chronic pain, nausea, fatigue, migraines, etc.
Mimosa
Mimosa strain is a Sativa-dominant hybrid resulting from a cross between Purple Punch and Clementine. Its Sativa characteristics make it the best early-morning strain of weed. However, you can also use it in the evening, just before bed. It will make you relax and unwind from the challenges faced during the day.
With a THC value of about 27%, Mimosa is one of the best marijuana strains. It benefits both recreational and medicinal users. It is ideal for treating anxiety, nausea, stress, mood swings, among others.
Zkittlez
Zkittlez strain is a well-balanced hybrid created by crossing GMO Cookies and OG Kush. From its lineage, you can certainly expect this to be a top marijuana strain. With a high THC of about 30% and 1% CBD, you can expect your thoughts to escalate very fast. Euphoria, happiness, and calmness set in soon after taking a few puffs of Zkittlez.
Zkittlez has a sweet, citrusy candy flavor that attracts people to it. Like all other top strains of weed on this list, Zkittlez is for both medicinal and recreational use.
Sour Diesel
Sour Diesel is a 90% Sativa and 10% Indica hybrid strain that has also won its place on our list of top 20 weed strains. This top marijuana strain has a high like no other. You can expect an exploding high with a burst of energy and creativity. It should be the best cannabis strain to take in the morning or during the day because it has no elements of couchlock.
White Widow
White Widow is one of the best hybrid weed strains with a THC value ranging from 18% to 25%. It is not only popular in Colorado as the weed strain but also recognized internationally. From its lineage of Brazil Sativa and South Indian Indica, White Widow has a cognitive-driven high. All users will still maintain their senses, but an overdose can result in a couchlock.
Trainwreck
Trainwreck strain is a Sativa-leaning hybrid created by crossing Mexican, Thai, and Afghani. This strain has both body high and mental high that make users feel energized and motivated. Its relaxing and numbing effects make it the best for relieving muscle spasms, chronic pain, anxiety, and inflammation.
Jack Herer
Jack Herer is one of the top Cannabis strains in Colorado and throughout the United States. It was named after a well-known cannabis activist, Jack Herer. This strain has lived up to its reputation. With happy, bubbly, and euphoric effects, it is the best weed strain to go for relieving stress-related conditions.
OG Kush
OG Kush is a hybrid strain with an Indica to Sativa ratio of 75:25 created by crossing Chemdawg and Hindu Kush. When consumed, OG Kush has a cerebral boost and heavy body high, making it ideal for fighting pain, nausea, insomnia, and stress. As the effects subside, you will be hit by a pang of hunger that will make you set your hands on anything edible.
Gelato
Gelato is a balanced hybrid weed strain known for a flavor profile of berry, citrus, lavender, and woody. This one of the best strains of weed is head heavy, which will leave you feeling happy and usually couch-locked. It has immense relaxing and calming effects, ideal for fighting chronic pain, fatigue, headaches, etc.
Purple Haze
Purple Haze is a Sativa-dominant hybrid resulting from a cross between Purple Thai and haze strains. It has a THC level ranging from 14% to 26%. When consumed, Purple Haze hits hard and fast. The high-cerebral stimulation associated with this strain makes it ideal for experienced users who can withstand it.
Purple Haze is highly potent, making it the best weed strain for treating depression, anxiety, chronic pain, among other medicinal conditions.
Wedding Cake
Wedding Cake is a hybrid strain resulting from a cross between Cherry Pie and Girl Scout cookies. It is famous for its sweet aroma, fruity flavor, and calming effects. Wedding Cake is one of the best strains of weed you can opt for to help you relieve symptoms of depression, chronic pain, multiple sclerosis, among others.
Granddaddy Purple
Granddaddy Purple strain is a 70% Indica and 30% Sativa with a THC level ranging from 20% to 27%. It is a flavorful weed strain packed with a dozen body effects that begin with an initial headrush and euphoria. Granddaddy Purple is the top marijuana strain recommended for relieving symptoms such as chronic pain, insomnia, muscle spasms, among others.
Super Lemon Haze
Super Lemon Haze is a hybrid marijuana strain with a Sativa to Indica ratio of 80:20. It originated from Washington but has become one of the world’s best strains of cannabis. Its head high will boost your energy and creativity. It is also associated with euphoria and intense happiness, making it the best marijuana strain for mood-boosting.
Durban Kush
Durban Kush is a perfectly balanced hybrid weed strain with a THC content of about 24%. It is potent marijuana that will hit you immediately with euphoria that grows with time and triggers happiness. This top-quality marijuana also has relaxing and other desirable effects, making it a top medical marijuana strain.
Banana Kush
Banana Kush is a slightly Indica-leaning hybrid strain famous for its fruity and tropical flavor profile and relaxing effects. It is a top-grade weed recommended for nighttime use because of the associated couchlock. Once taken, Banana Kush wipes away all your worries and makes you go into a peaceful deep sleep.
Grape Pie
Grape Pie is an Indica-dominant hybrid weed strain characterized by a rich, fruity berry pie flavor. The head high of this high-end weed strain starts with a light tingly effect that quickly expands to take over your entire body. This leaves you euphoric and relaxed.
Chemdawg
Chemdawg is a hybrid weed strain with a near balance between Indica and Sativa. Despite its relatively low THC level of about 19%, this is one of the high-grade weeds with a strong cerebral high. Its potency and sleepy properties have made it a popular cannabis strain among medicinal users. Medicinally, Chemdawg is ideal for treating insomnia, appetite loss, chronic pain, depression, etc.
Purple Punch
Purple Punch is one of the top-shelf weed names that you cannot miss in the dispensary in Colorado. This Indica-heavy hybrid has a slam of euphoria and intense head high that can knock you out in no time. Apart from the couch-lock effect, Purple Punch is also uplifting, relaxing, and sedating. You need it to effectively fight insomnia, appetite loss, depression, and chronic pain.
Cherry Diesel
Cherry Diesel is a cross between Cherry OG and Turbo Diesel, resulting in a 50:50 balance of Indica and Sativa genes. It is probably one of the top medical marijuana strains for users who want both effects of Indica and Sativa. The Cherry Diesel high begins with mild tingly energy, focus, and creativity. If you are looking for the best quality weed that will not knock you down, this one might be the best for you.